Neuroglobin Expression in the Mammalian Auditory System
نویسندگان
چکیده
منابع مشابه
Neuroglobin expression in ischemic stroke.
BACKGROUND AND PURPOSE We investigated whether neuroglobin, a neuronal protein that protects neurons from hypoxic-ischemic injury, is upregulated in ischemic stroke. METHODS Neuroglobin immunoreactivity was measured in brain tissue from control subjects and patients with ischemic stroke. RESULTS Neuroglobin was detected in several brain areas, and its expression was increased in the cortica...
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Neuroglobin (Ngb) is an intracellular, oxygen-binding neuronal protein with protective effects against ischemia and related pathological processes. To identify small molecules capable of inducing Ngb protein expression, which might have therapeutic benefit, we examined Ngb expression by Western blot in cultured HN33 (mouse hippocampal neuron ! N18TG2 neuroblastoma) cells. In addition to deferox...
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Astrocytes play an important role in physiological, metabolic, and structural functions, and when impaired, they can be involved in various pathologies including Alzheimer, focal ischemic stroke, and traumatic brain injury. These disorders involve an imbalance in the blood flow and nutrients such as glucose and lactate, leading to biochemical and molecular changes that cause neuronal damage, wh...
متن کاملPharmacological Induction of Neuroglobin Expression
Neuroglobin (Ngb) is an intracellular, oxygen-binding neuronal protein with protective effects against ischemia and related pathological processes. To identify small molecules capable of inducing Ngb protein expression, which might have therapeutic benefit, we examined Ngb expression by Western blot in cultured HN33 (mouse hippocampal neuron ! N18TG2 neuroblastoma) cells. In addition to deferox...
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ژورنال
عنوان ژورنال: Molecular Neurobiology
سال: 2015
ISSN: 0893-7648,1559-1182
DOI: 10.1007/s12035-014-9082-1